乳脂球表皮生長因子8(MFGE8)重組蛋白
Recombinant Milk Fat Globule EGF Factor 8 (MFGE8)
HMFG; MFGM; SED1; BA46; EDIL1; OAcGD3S; SPAG10; hP47; Medin; Lactadherin; Sperm Associated Antigen 10; Sperm Surface Protein hP47; Milk fat globule-EGF factor 8
- 編號URPB286Mu01
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜, 分泌
- 預測分子量30.3kDa
- 實際分子量30kDa(差異分析請參閱說明書)
- 片段與標簽Ile159~Ser417 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點8.3
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 588 ¥ 1470 ¥ 2940 ¥ 8820 ¥ 22050
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure . Gene Sequencing (extract)
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SDS-PAGE圖
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通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務
相關產(chǎn)品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| URPB286Mu02 | 乳脂球表皮生長因子8(MFGE8)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UAPB286Mu01 | 乳脂球表皮生長因子8(MFGE8)活性蛋白 | Cell?culture;?Activity?Assays. |
| URPB286Mu01 | 乳脂球表皮生長因子8(MFGE8)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB286Mu01 | 乳脂球表皮生長因子8(MFGE8)多克隆抗體 | WB |
| UPAB286Mu02 | 乳脂球表皮生長因子8(MFGE8)多克隆抗體 | WB; IHC; ICC; IP. |
| USEB286Mu | 乳脂球表皮生長因子8(MFGE8)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMB286Mu | 乳脂球表皮生長因子8(MFGE8)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Fertility and Sterility | Tumor necrosis factor α up-regulates endometrial milk fat globule-epidermal growth factor 8 protein production via nuclear factor κB activation, resulting in cell migration of epithelial cells. [Pubmed: 24262600] |
| U.S. Patent Application | Biomarker for amyloid-b-related neurological disorders [US20130302838] |
| IUBMB Life. | Elevated serum milk fat globule-epidermal growth factor 8 levels in type 2 diabetic patients are suppressed by overweight or obese status. [pubmed:28067023] |
| Journal of diabetes investigation | Circulating milk fat globule-epidermal growth factor 8 levels are increased in pregnancy and gestational diabetes mellitus. [pubmed:28035763] |
| The Journal of Steroid Biochemistry and Molecular Biology | Modifications of Western-type diet regarding protein, fat and sucrose levels as modulators of steroid metabolism and activity in liver [pubmed:27471150] |
| Journal of Steroid Biochemistry and Molecular Biology | Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling [pubmed:28263910] |
| Oncotarget | Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response. [pubmed:28489606] |
| Molecular and Cellular Neuroscience | TGF-β1 enhances phagocytic removal of neuron debris and neuronal survival by olfactory ensheathing cells via integrin/MFG-E8 signaling pathway [10.1016/j.mcn.2017.08.006] |
| Amyloid | Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein [Pubmed: 31615282] |
| clinical and translational medicine | Milk fat globule EGF factor 8 restores mitochondrial function via integrin?\medicated activation of the FAK?\STAT3 signaling pathway in acute pancreatitis [33634976] |
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