我吃西红柿,辰东

分泌型卷曲相關(guān)蛋白5(SFRP5)多克隆抗體

Polyclonal Antibody to Secreted Frizzled Related Protein 5 (SFRP5)

SARP3; Secreted Apoptosis Related Protein 3; Frizzled-related protein 1b

信號轉(zhuǎn)導(dǎo)

編號UPAC842Hu01
物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來源多抗制備
宿主兔
效價-
Ig類型 IgG
純化方式抗原特異性親和純化
標(biāo)記物無標(biāo)記物
免疫原 RPC842Hu01-分泌型卷曲相關(guān)蛋白5(SFRP5)重組蛋白
緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
性狀液體
濃度0.33mg/mL
且適物種-
應(yīng)用IHC
如果抗體需用于流式細(xì)胞術(shù)，請參見流式抗體。
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規(guī)格 20μl100μl 200μl 1ml 10ml
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

DAB staining on IHC-P; Samples: Human Glioma Tissue; Primary Ab: 20μg/ml Rabbit Anti-Human SFRP5 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
DAB staining on IHC-P;
Samples: Human Stomach Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Human SFRP5 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
DAB staining on IHC-P;
Samples: Human Liver Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Human SFRP5 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)

Figure. Western Blot; Sample: Recombinant SFRP5, Human.

通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對SFRP5的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別SFRP5。

用法

Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

贈品

增值服務(wù)

抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
 細(xì)胞和組織染色液
 抗體陽性對照品
 組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實驗服務(wù)
免疫組織化學(xué)(IHC)實驗服務(wù)
免疫細(xì)胞化學(xué)(ICC)實驗服務(wù)
流式細(xì)胞術(shù)(FCM)實驗服務(wù)
免疫沉淀(IP)實驗服務(wù)
免疫熒光(IF)實驗服務(wù)
緩沖液
 DAB顯色試劑盒
 SABC試劑盒
 長臂生物素標(biāo)記試劑盒
 實時熒光定量PCR實驗服務(wù)

參考文獻(xiàn)

雜志	參考文獻(xiàn)
Diabetes Research and Clinical Practice	Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance [PubMed: 23290274]
European Journal of Clinical Investigation	Sfrp5 correlates with insulin resistance and oxidative stress [PubMed: 23398169]
Pediatric Research	Balanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children [Pubmed: 24603290]
Clin Endocrinol (Oxf).	SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children [Pubmed: 24330025]
The Journal of Clinical Endocrinology & Metabolism	Circulating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans [Pubmed: 23185036]
Atherosclerosis	Low serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease [Pubmed: 24530778]
PLoS One.	Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation [Pubmed:Pmc4072672]
J Clin Endocrinol Metab.	Activation of noncanonical Wnt signaling through WNT5A in visceral adipose tissue of obese subjects is related to inflammation [Pubmed:24840810]
Oncology Letters	Serum secreted frizzled?related protein 5 levels differentially decrease in patients with hepatitis B virus?associated chronic infection and hepatocellular carcinoma [Pubmed:25120720]
Diabetes Metab Res Rev.	Circulating SFRP5 levels are elevated in drug‐na?ve recently diagnosed type 2 diabetic patients as compared with prediabetic subjects and controls [Pubmed:25139699]
Clinical & Experimental Immunology	The wingless-related integration site-5a/secreted frizzled-related protein-6 system is dysregulated in human sepsis [Pubmed:25382802]
Diabetes Metab Res Rev	Circulating SFRP5 levels are elevated in drug-na [PubMed: 25139699]
J Matern Fetal Neonatal Med	Prediction of gestational diabetes mellitus by first trimester serum secreted frizzle-related protein-5 levels [PubMed: 26100762]
Eur J Clin Invest	Sfrp5 associates with beta-cell function in humans [Pubmed:27019073]
Osteoporosis International	Bone marrow sFRP5 level is negatively associated with bone formation markers [pubmed:27986984]
Diabetes/Metabolism Research and Reviews	Plasma Sfrp5 levels correlate with determinants of the metabolic syndrome in Chinese adults [pubmed:28303637]
Cardiovascular Diabetology	Inverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study [pubmed:28851362]
Arteriosclerosis, Thrombosis, and?Vascular Biology?	Effect of SFRP5 (Secreted Frizzled–Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With?… [Pubmed:29674475]
Obesity	Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans [Pubmed:29427376]
J Bas Res Med Sci	Decreased level of the anti-inflammatory adipokines, secreted frizzled-related protein 5 and adiponectin, in high cholesterol diet-induced atherosclerotic rats [article-1-352-en.pdf]
Molecular?Biology?Reports	The effect of serum and follicular fluid secreted frizzle-related protein-5 on in vitro fertilization outcomes in patients with polycystic ovary syndrome [Pubmed: 30194556]
	Macrophage LRP1 promotes diet-induced hepatic inflammation and metabolic dysfunction by modulating Wnt signaling []
British?Journal Of Nutrition	A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile [Pubmed: 30375290]
J Clin Endocrinol Metab	Role of wnt5a in Metabolic Inflammation in Humans [Pubmed: 30137542]
Frontiers in Endocrinology	Association of Adipocytokines With Carotid Intima Media Thickness and Arterial Stiffness in Obstructive Sleep Apnea Patients [Pubmed: 32300333]
CLINICAL BIOCHEMISTRY	Sfrp5/Wnt5a and Leptin/adiponectin levels in the serum and the periarterial adipose tissue of patients with peripheral arterial occlusive disease [Pubmed: 33188773]
Sao Paulo Medical Journal	Association of serum levels of secreted frizzled-related protein 5 and Wnt member 5a with glomerular filtration rate in patients with type 2 diabetes mellitus and … [Pubmed: 32491086]
Kidney Blood Press Res	Secreted Frizzled-Related Protein 5 Ameliorates Vascular Calcification in a Rat Model of Chronic Kidney Disease through the Wnt/β-Catenin Pathway [34469882]
Cytokine	Association of serum uromodulin with adipokines in dependence of type 2 diabetes [34920231]
PLoS One	Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study [Pubmed:34990470]
JMIR Res Protoc	Investigating New Sensory Methods Related to Taste Sensitivity, Preferences, and Diet of Mother-Infant Pairs and Their Relationship With Body Composition?… [Pubmed:35475790]
Diabetology	Early Pregnancy Serum Concentration of Secreted Frizzled-Related Protein 4, Secreted Frizzled-Related Protein 5, and Chemerin in Obese Women Who Develop?… []

留言咨詢

編號	適用物種：Homo sapiens (Human，人)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
URPC842Hu01	分泌型卷曲相關(guān)蛋白5(SFRP5)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
URPC842Hu02	分泌型卷曲相關(guān)蛋白5(SFRP5)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
URPC842Hu03	分泌型卷曲相關(guān)蛋白5(SFRP5)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
UPAC842Hu01	分泌型卷曲相關(guān)蛋白5(SFRP5)多克隆抗體	IHC
UPAC842Hu03	分泌型卷曲相關(guān)蛋白5(SFRP5)多克隆抗體	WB
UPAC842Hu02	分泌型卷曲相關(guān)蛋白5(SFRP5)多克隆抗體	WB
ULAC842Hu71	分泌型卷曲相關(guān)蛋白5(SFRP5)多克隆抗體(生物素標(biāo)記)	WB
UMAC842Hu22	分泌型卷曲相關(guān)蛋白5(SFRP5)單克隆抗體	WB; IHC; ICC; IP.
ULAC842Hu72	分泌型卷曲相關(guān)蛋白5(SFRP5)單克隆抗體(生物素標(biāo)記)	WB; IHC; ICC.
USEC842Hu	分泌型卷曲相關(guān)蛋白5(SFRP5)檢測試劑盒(酶聯(lián)免疫吸附試驗法)	Enzyme-linked immunosorbent assay for Antigen Detection.
UWEC842Hu	分泌型卷曲相關(guān)蛋白5(SFRP5)檢測試劑盒(酶聯(lián)免疫吸附試驗法,寬范圍)	Enzyme-linked immunosorbent assay for Antigen Detection.
UHEC842Hu	分泌型卷曲相關(guān)蛋白5(SFRP5)檢測試劑盒(酶聯(lián)免疫吸附試驗法,高敏型)	Enzyme-linked immunosorbent assay for Antigen Detection.
ULMC842Hu	分泌型卷曲相關(guān)蛋白5(SFRP5)等多因子檢測試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.